The “number needed to treat” turns 20 — and continues to be used and misused
An excellent article discussing the number needed to treat (NNT).
The baseline risk is important…
For example, although the mortality relative risk reduction with antihypertensive therapy is similar across risk strata (about 9%–12%), the number needed to treat for antihypertensive therapy to prevent 1 death over 5 years ranges from 1157 in healthy young women to 17 in older men with other cardiovascular risk factors.